|Calcium min||16 g||14%|
|Calcium max||18 g||16%|
|Magnesium min||3,400 mg||3%|
|Zinc min||97 mg||860 ppm|
|Copper min||43 mg||380 ppm|
|Manganese min||41 mg||360 ppm|
|Vitamin D3 min||3,750 IU||15,000 IU/lb|
|Contains no added selenium.|
More information about the ingredients in BoneWise
Calcium from Lithothamnion
BoneWise contains a unique form of calcium, a calcareous marine alga know as Lithothamnion, which is rich in highly digestible calcium and trace minerals. Lithothamnion contains three crystalline forms of calcium: calcite, aragonite, and vaterite, as compared to calcium carbonate (a common source of calcium) that only contains calcite. The minerals found in Lithothamnion are arranged in a distinctive honeycomb construction that increase digestibility. Because of its varied crystalline forms and honeycomb structure, Lithothamnion provides a large surface upon which digestive enzymes can act, allowing for the optimal release and uptake of minerals over extended periods of time. Lithothamnion contains the trace minerals magnesium, boron, silicon, zinc, and manganese, all of which play a role in bone formation and remodeling.
Research conducted at Michigan State University on two groups of yearlings-one supplemented with Lithothamnion, the other (the control) supplemented with calcium carbonate-revealed that the Lithothamnion group showed significant difference in blood markers of bone metabolism and bone density as compared to the control group. Osteocalcin, which is a measure of bone formation, and CTX-1, a measure of bone resorption, were both higher in the supplemented group, indicating a positive effect on bone metabolism. At the end of the supplementation period, the Lithothamnion supplement group presented with 11% greater bone mineral content.
Vitamin D is critical to mineral metabolism and bone growth. It facilitates the absorption of calcium in the small intestine by stimulating proteins known as calcium transporters. The transporters move the calcium out of the lumen of the intestine, across the epithelial cells, and into the bloodstream. In the bone, vitamin D regulates the balance of calcium and phosphorous necessary for proper bone mineralization.
Yeast positively contributes to mineral absorption in a variety of ways. It supports enhanced mineral absorption by improving microbial metabolism of enzymes and vitamins. Calcium absorption by enterocytes (cells in the intestinal lining) is stimulated in the presence of yeast, and microbial enzymes improve phosphorus absorption.
Research has demonstrated that yeast helps to maintain and stabilize the intestinal microflora. A stabilized microflora supports optimal gut tissue health and function. Healthy gut tissues exhibit an improved capacity to absorb nutrients.