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Denosyl 225 mg for Medium Dogs 13-34 lbs, 90 Tablets

Item: DENO225-3PK
Availability: In Stock

Was: $109.99$83.97You Save: $26.02!(24%)


Denosyl 225 mg is a nutritional supplement that helps minimize a variety of liver problems in medium-sized dogs. It has also been shown to improve liver health and function by protecting and repairing liver cells.


  • Dogs 13-34 pounds

Key Features

  • #1 Veterinarian Recommended
  • Effective Liver Protection
  • Available for Dogs & Cats of All Sizes
  • Wide Margin of Safety
  • Easy Administration Through Tablet Form


S-Adenosylmethionine, 225 mg

Useful Information

Dosage Table

Body WeightDaily Amount
13 to 34 pounds (6-15.5 kg)1 Tablet

The number of tablets can be gradually reduced or may be increased at any time depending on the pet's needs.

Daily administration may also be calculated based on 20 mg/kg of body weight and rounded to the closest tablet size or combination of sizes.


  • Tablets should be given on an empty stomach at least one hour before feeding for optimal absorption
  • If your pet requires more than 1 daily tablet, you may divide the daily total between morning and night
  • Denosyl may be disguised in a small bite of food if needed
  • Administer 3-6 cc of water immediately following any tablet administration to speed passage of the tablet into the stomach
  • Storage

    Store in a cool, dry place. Keep tablets in original blister pack until used. Tablets are sensitive to moisture and extreme heat and should not be split or crumbled.


    Denosyl is available enteric-coated tablets for cats and dogs.
    Your veterinarian will advise you as to the amount to initially administer. Depending on your petís response and status, your veterinarian may eventually adjust this amount to meet your petís individual needs. Remember, Denosyl enteric-coated tablets should not be broken. When increasing or decreasing their administration, adjustments should be done in full tablet increments. Some pets are given Denosyl only for a short period of time, although Denosyl may be used longer in other animals.
    While response varies, owners may note a change in their petís appetite, activity, and attitude.
    Your veterinarian will likely recommend follow-up examinations, blood work, and/or other laboratory work to check on how well your pet is doing with Denosyl and how it may be helping to support your petís liver function.
    Denosyl has been shown to be well-tolerated by both dogs and cats with a wide margin of safety.
    Yes, your veterinarian may recommend combining Denosyl with other products and/or dietary modifications. One such product is called Marinģ Plus, which can be administered with Denosyl for additional liver health support. There are no known adverse interactions of Denosyl with drugs or other supplements. Denosyl may even protect against negative effects on the liver caused by some medications.
    While other S-Adenosylmethionine (SAMe) products are available, there can be a significant variance in product quality and activity levels of SAMe. Denosyl is produced using high-quality, researched ingredients and under strict manufacturing standards.
    Administration of methionine is not recommended. Providing high levels of methionine to pets with liver compromise may not increase the production of natural S-Adenosylmethionine and has been shown in some cases to increase liver damage.

    Customer Reviews

    Review Summary
    3 Reviews
    100% (3)
    0% (0)
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    0% Recommend this product (0 of 3 responses)
    By Randhil
    November 16, 2011
    AFAICT you\'ve coevred all the bases with this answer!
    By Mary S.
    Denosyl Keeps my Sheltie Healthy
    January 25, 2011
    Denosyl was recommended by a veterinarian specialist in internal problems to help regulate liver enzyme levels in my sheltie, Sara. She has vacular liver diseas, as well as an undersized liver, and became very ill at age one. Since then,she\'s been doing well and takes Denosyl along with Marin daily. She is now eight years old, and we are pleased that this drug has heped her condition.
    February 10, 2009
    My Minn Pinn was close to dying from a bad liver 2 years ago. After many tests and fluids and medications, one of which was Denosyl, he is doing great! I have decided to keep in on Denosyl for ever! Through the advice of my Vet of course. I give him 1 pill a day in the morning the 225 mg and this has kept his liver functioning properly!
    I love the prices on Healthy Pets also.. can\'t bet them!

    Customer Q&A

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