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|  | Frontline PLUS for Dogs and Cats New Frontline Plus is the improved formula which now contains a compound to kill flea eggs as well. This will theoretically provide better flea control compared to regular Frontline. If you already have adequate flea/tick control with regular Frontline, you may want to continue with the regular formula.
Frontline Plus is based on Fipronil, an insecticide that disrupts the insect's central nervous system by blocking the passage of Chloride ions through the GABA receptor and the glutamate receptor. The contaminated nerves and muscles of the insect become hyperexcited poisoning the insect.
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