Denosyl is recommended to improve hepatic glutathione levels to help maintain and protect liver function. 45% of dogs and cats with liver problems have a low hepatic glutathione level. Denosyl has been shown to increase hepatic glutathione levels in cats and dogs. Glutathione is a potent antioxidant that protects hepatic cells.
For optimal absorption, tablets should be given on an empty stomach, at least one hour before feeding, as the presence of food decreases the absorption of S-Adenosylmethionine. When giving more than one tablet, the total daily dose may be provided as a morning and evening dose. For example, a daily dose of three tablets could be divided into two tablets in the morning and one tablet in the evening.FELINE AND CANINE DENOSYL ADMINISTRATION GUIDE
||Total daily administration
and tablet size
|Up to 12 pounds (5.5 kg)
||One tablet of 90 mg
|13 to 34 pounds (6-15.5 kg)
||One tablet of 225mg
|35 to 65 pounds (16 to 29.5 kg)
||One tablet of 425 mg
|66 to 120 pounds (30 to 54.5 kg)
||Two tablets of 425 mg
|Over 120 pounds (54.5 kg +)
||Three tablets of 425 mg
The number of tablets can be gradually reduced or may be increased at any time depending on the pet's needs.